Previous research conducted at Purdue University at beginning flowering and pod set growth stages updated defoliation loss tables for current variety genetics, management practices, and climate. However, it also brought into question the defoliation loss tables for later reproductive stage soybean. This project occured in Iowa and Indiana (Shaun Casteel). Defoliation events were timed at full pod set (R4) and beginning seed fill (R5) reproductive stages. Grain yield and composition were determined at the end of the growing season as well as canopy closure and crop reflectance following defoliation.